Prolotherapy & Prolozone Therapy
A Revolutionary Approach to Pain Relief
Prolotherapy and Prolozone Therapy are non-surgical regenerative treatments designed to repair damaged ligaments, tendons, and joints. These therapies work by stimulating the body's natural healing response, making them powerful alternatives to pain management medications and surgery.
How It Works
- Prolotherapy: A natural irritant (like dextrose) is injected into weakened joints or connective tissues, triggering inflammation and promoting collagen production for long-term tissue repair [1].
- Prolozone Therapy: Combines prolotherapy with ozone (O3) injections, significantly enhancing oxygen delivery to tissues, reducing inflammation, and accelerating healing [2].
What Conditions Can It Treat?
- Chronic joint pain (knees, shoulders, hips, and spine)
- Osteoarthritis & degenerative joint diseases
- Ligament & tendon injuries
- Herniated discs & back pain
- Sports injuries & repetitive strain conditions
- TMJ dysfunction & carpal tunnel syndrome
What to Expect from Prolotherapy & Prolozone Therapy
- Treatments are quick (15–30 minutes) and require little to no downtime.
- Most patients experience improvement after just a few sessions.
- Minimal discomfort with long-lasting relief from pain and inflammation.
How Clinics Can Leverage Prolotherapy & Prolozone to Boost Patient Outcomes and Revenue
- Expand Your Service Offerings: Integrate Prolotherapy and Prolozone into your practice to provide non-surgical, regenerative solutions for chronic pain, joint issues, and musculoskeletal injuries—meeting growing patient demand for effective, minimally invasive care.
- Improve Patient Results: These therapies stimulate the body’s natural healing mechanisms, leading to faster recovery, reduced inflammation, and long-term relief—translating to happier, more loyal patients.
- Tap Into the Science: Gain confidence with peer-reviewed research and clinical evidence that supports the use of Prolotherapy and Prolozone in functional, integrative, and sports medicine practices [1], [2], [3].
- Upskill Your Team: Train staff on proper protocols, injection techniques, and treatment planning through expert-led webinars, workshops, or certification programs—ensuring safe and effective delivery.
- Drive New Revenue Streams: Offer high-value, cash-based regenerative treatments that require minimal equipment and can be seamlessly added to your existing services—enhancing profitability without major overhead.
- Stand Out in a Competitive Market: Differentiate your clinic by offering advanced regenerative solutions that align with the wellness industry’s shift toward root-cause, results-driven care.
FAQs for Clinics Considering Offering Prolotherapy & Prolozone
Is this a profitable service for my clinic?
Yes, prolotherapy and prolozone therapy are typically cash-based services, meaning they offer higher profit margins than insurance-based treatments. With minimal equipment costs and repeat patient visits, they can be a valuable revenue stream.
What are the patient demand trends?
Interest in non-surgical pain relief and regenerative medicine is rapidly growing. Many patients prefer minimally invasive, drug-free options for chronic pain management, making these therapies highly sought after.
What training or certifications are required?
Training varies by region, but most providers (MDs, DOs, DCs, NPs) can learn these techniques through certification courses and hands-on workshops. Our course provides comprehensive training for practitioners looking to integrate these treatments.
What is the cost of integrating this into my clinic?
Initial training & certification: Varies based on provider credentials.
Supplies & equipment: Minimal, typically involving syringes, ozone generators, and injectables.
Ongoing costs: Primarily consumable supplies (dextrose, oxygen, ozone kits).
Supplies & equipment: Minimal, typically involving syringes, ozone generators, and injectables.
Ongoing costs: Primarily consumable supplies (dextrose, oxygen, ozone kits).
Are these treatments covered by insurance?
Most Prolotherapy & Prolozone treatments are cash-based, which eliminates insurance hurdles and provides clinics with immediate revenue.
How does this compare to other regenerative treatments?
More affordable than PRP and stem cell therapy.
Less invasive with quicker patient recovery times.
Can be combined with PRP, chiropractic, acupuncture, and functional medicine for enhanced results.
Less invasive with quicker patient recovery times.
Can be combined with PRP, chiropractic, acupuncture, and functional medicine for enhanced results.
Who are the ideal candidates for these treatments?
Patients with chronic joint pain or sports injuries.
Individuals seeking non-surgical pain relief.
Those looking to avoid medications or steroids.
Individuals seeking non-surgical pain relief.
Those looking to avoid medications or steroids.
How do I educate my patients about these therapies?
Clinics can use educational materials, webinars, and free eBooks to introduce patients to these regenerative therapies. Our free eBook provides an in-depth guide to help practitioners educate their patients.
References
- Rabago D, Zgierska A, Fortney L, et al. Hypertonic dextrose injections (prolotherapy) for knee osteoarthritis: results of a single-arm uncontrolled study with 1-year follow-up. J Altern Complement Med. 2012;18(4):408-14.
- Jeyaraman M, et al. Ozone therapy in musculoskeletal medicine: a comprehensive review. Eur J Med Res. 2024;29(398).
- Eroglu A, Sari A, Durmis B. Comparison of the efficacy of dextrose prolotherapy and ozone in patients with knee osteoarthritis: a randomized cross-sectional study. Appl Sci. 2021;11(21):9991.
Watch These Testimonials From Our Other Events!
Explore tip skills and certifications
Leadership
Leadership
Management Skills
Project Management
Personal Productivity
Emotional Intelligence
Communication
Communication Skills
Presentation Skills
Public Speaking
Writing
PowerPoint
Leadership
Leadership
Management Skills
Project Management
Personal Productivity
Emotional Intelligence
Newsletter
Get a daily email featuring the latest talk, plus a quick mix of trending content.
Reviewed by
Heather Scott-Meyer, MSN, FNP-C
Stanford Cardiothoracic Surgery
Weekend Health Medical Weight Loss
George Holmes University Professor
Professor of Biochemistry, emerita, University of Nebraska-Lincoln
Disclaimer: This content is for educational and informational purposes only. It does not constitute medical advice or replace consultation with a licensed provider—always consult your healthcare provider.
Disclaimer: Content provided by MedBio Institute is for educational purposes only and is intended for licensed healthcare professionals. It is not medical advice. Read full disclaimer.