Learn > Regenerative Therapies > Prolotherapy & Prolozone Therapy

Prolotherapy & Prolozone Therapy

A Revolutionary Approach to Pain Relief

What is Prolotherapy & Prolozone Therapy?

Prolotherapy and Prolozone Therapy are non-surgical regenerative treatments designed to repair damaged ligaments, tendons, and joints. These therapies work by stimulating the body's natural healing response, making them powerful alternatives to pain management medications and surgery.

How It Works

Prolotherapy:

A natural irritant (like dextrose) is injected into weakened joints or connective tissues, triggering inflammation and promoting collagen production for long-term tissue repair.

A natural irritant (like dextrose) is injected into weakened joints or connective tissues, triggering inflammation and promoting collagen production for long-term tissue repair.

Prolozone Therapy:

Combines prolotherapy with ozone (O3) injections, significantly enhancing oxygen delivery to tissues, reducing inflammation, and accelerating healing.

What Conditions Can It Treat?

These treatments are commonly used for:

  • Chronic joint pain (knees, shoulders, hips, and spine)

  • Osteoarthritis & degenerative joint diseases

  • Ligament & tendon injuries

  • Herniated discs & back pain

  • Sports injuries & repetitive strain conditions

  • TMJ dysfunction & carpal tunnel syndrome

Why Learn About Prolotherapy & Prolozone?

Expand Your Knowledge – Stay ahead in regenerative medicine.

Understand Non-Surgical Options – Learn how these therapies support tissue healing

Science-Backed & Effective – Discover clinical research behind their success.

Enhance Your Practice – Gain insights into implementing these therapies.

What to Expect from Treatment

Treatments are quick (15-30 minutes) and require little to no downtime.

Most patients experience improvement after just a few sessions.

Minimal discomfort with long-lasting relief from pain and inflammation.

FAQs for Wellness Clinics Considering These Therapies

Is this a profitable service for my clinic?

Yes, prolotherapy and prolozone therapy are typically cash-based services, meaning they offer higher profit margins than insurance-based treatments. With minimal equipment costs and repeat patient visits, they can be a valuable revenue stream.

What are the patient demand trends?

Interest in non-surgical pain relief and regenerative medicine is rapidly growing. Many patients prefer minimally invasive, drug-free options for chronic pain management, making these therapies highly sought after.

What training or certifications are required?

Training varies by region, but most providers (MDs, DOs, DCs, NPs) can learn these techniques through certification courses and hands-on workshops. Our course provides comprehensive training for practitioners looking to integrate these treatments.

FAQ image

What is the cost of integrating this into my clinic?

Initial training & certification: Varies based on provider credentials.

Supplies & equipment: Minimal, typically involving syringes, ozone generators, and injectables.

Ongoing costs: Primarily consumable supplies (dextrose, oxygen, ozone kits).

Are these treatments covered by insurance?

Most Prolotherapy & Prolozone treatments are cash-based, which eliminates insurance hurdles and provides clinics with immediate revenue.

How does this compare to other regenerative treatments?

More affordable than PRP and stem cell therapy.

Less invasive with quicker patient recovery times.

Can be combined with PRP, chiropractic, acupuncture, and functional medicine for enhanced results.

Who are the ideal candidates for these treatments?

Patients with chronic joint pain or sports injuries.

Individuals seeking non-surgical pain relief.

Those looking to avoid medications or steroids.

How do I educate my patients about these therapies?

Clinics can use educational materials, webinars, and free eBooks to introduce patients to these regenerative therapies. Our free eBook provides an in-depth guide to help practitioners educate their patients.

Want to Dive Deeper?

Download our comprehensive guide on Prolotherapy & Prolozone Therapy to explore case studies, research, and practical applications for your practice.

Clinical Evidence Supporting These Therapies

Prolotherapy:

  • University of Wisconsin Research: A randomized controlled trial demonstrated that participants receiving dextrose prolotherapy for knee osteoarthritis experienced significant improvement in pain and function compared to control groups. ​mdpi.com openmedicalpublishing.org

  • Mayo Clinic Study: The Mayo Clinic conducted a study on dextrose prolotherapy, highlighting its potential benefits for patients with knee osteoarthritis. ​mayo.edu

Prolozone Therapy:

  • Comprehensive Review: A study published in the European Journal of Medical Research reviewed the application of ozone therapy in musculoskeletal medicine, noting its anti-inflammatory and analgesic effects in various conditions, including osteoarthritis. biomedcentral.com

  • Comparative Study: A clinical trial compared the efficacy of dextrose prolotherapy and ozone therapy in patients with knee osteoarthritis, finding both treatments effective in reducing pain and improving function. mdpi.com

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Content provided by MedBio Institute is for educational purposes only and is intended for licensed healthcare professionals. It is not medical advice. Read full disclaimer.